Across adult study groups, a year of testosterone suppression and estrogen lowered testosterone by a median of about 96%, but lowered hemoglobin by 7%, muscle size by 6%, lean mass by 4%, and left strength essentially unchanged (median +0.5%; groups ranged from -7% to +2%).
Error bars show the range of each estimate (ciLow to ciHigh).
| ciHigh | ciLow | estimate | intervalType | label | measure | method | n | order | unit |
|---|---|---|---|---|---|---|---|---|---|
| -48.8 | -97.8 | -95.6 | range | Testosterone | testosterone | Median of the percentage changes in the included study groups; the range is the lowest and highest study group. | 12 | 1 | % change after about 12 months |
| -4.6 | -14 | -7 | range | Hemoglobin (red blood cells) | hemoglobin | Median of the percentage changes in the included study groups; the range is the lowest and highest study group. | 5 | 2 | % change after about 12 months |
| -1.5 | -9.5 | -6.4 | range | Muscle size | muscleArea | Median of the percentage changes in the included study groups; the range is the lowest and highest study group. | 4 | 3 | % change after about 12 months |
| -0.8 | -5.4 | -4 | range | Lean body mass | leanMass | Median of the percentage changes in the included study groups; the range is the lowest and highest study group. | 8 | 4 | % change after about 12 months |
| 2 | -7.1 | 0.5 | range | Strength | strength | Median of the percentage changes in the included study groups; the range is the lowest and highest study group. | 5 | 5 | % change after about 12 months |